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1

Nivolumab ± ipilimumab treatment (Tx) efficacy, safety, and biomarkers in patients (Pts) with metastatic colorectal cancer (mCRC) with and without high microsatellite instability (MSI-H): results from the CheckMate-142 study

Overman, M.J., Kopetz, S., Lonardi, S., McDermott, R., Leone, F., Leach, J., Lenz, H-J., Hendlisz, A., Morse, M., Garcia-Alfonso, P., Desai, J., Hill, A., Moss, R.A., Goldberg, M.V., Lin, C-S., Tang,

Journal:

Annals of Oncology

Année:

2016

Langue:

english

Fichier:

PDF, 89 KB

english, 2016

2

Association of baseline absolute neutrophil counts and survival in patients with metastatic colorectal cancer treated with second-line antiangiogenic therapies: exploratory analyses of the RAISE trial and validation in an electronic medical record data set

Grothey, Axel, Yoshino, Takayuki, Bodoky, Gyorgy, Ciuleanu, Tudor, Garcia-Carbonero, Rocio, García-Alfonso, Pilar, Van Cutsem, Eric, Muro, Kei, Mytelka, Daniel S, Li, Li, Lipkovich, Olga, Hsu, Yanzhi,

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2018

3

Patency rates of dysfunctional central hemodialysis venous catheter: Comparison between catheter exchange alone and catheter exchange with fibrin sheath angioplasty

Maldonado-Cárceles, A.B., García-Medina, J., García-Alfonso, J.J., Árense-Gonzalo, J.J., Torres-Cantero, A.M.

Journal:

Diagnostic and Interventional Imaging

Année:

2018

Langue:

english

Fichier:

PDF, 855 KB

english, 2018

4

[IEEE 2018 IEEE 2nd Colombian Conference on Robotics and Automation (CCRA) - Barranquilla (2018.11.1-2018.11.3)] 2018 IEEE 2nd Colombian Conference on Robotics and Automation (CCRA) - Comparison of uncertainty analysis of the Montecarlo and Latin Hypercube algorithms in a camera calibration model

Garcia-Alfonso, Harold, Cordova-Esparza, Diana-Margarita

Année:

2018

Langue:

english

Fichier:

PDF, 5 KB

english, 2018

5

Treatment of patients with advanced gastric carcinoma with the combination of etoposide plus oral tegafur modulated by uracil and leucovorin: A phase II study of the ONCOPAZ Cooperative Group

J. Feliu, M. González Barón, C. García-Girón, E. Espinosa, P. García-Alfonso, J. Belón, E. Blanco, P. Garrido, A. Ordóñez, J. Gómez-Navarro, P. Zamora

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 562 KB

english, 1996

6

Horse-liver glutathione reductase: Purification and characterization

Concepción Garcìa-Alfonso, Emilia Martìnez-Galisteo, Antonio Llobell, J.Antonio Bárcena, Juan lÓpez-Barea

Journal:

International Journal of Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 856 KB

english, 1993

7

Regulation of horse-liver glutathione reductase

Concepción García-Alfonso, Emilia Martínez-Galisteo, Antonio Llobell, J.Antonio Bárcena, Juan López-Barea

Journal:

International Journal of Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 917 KB

english, 1993

8

Integration of panitumumab into the treatment of colorectal cancer

Cristina Gravalos, Javier Cassinello, Pilar García-Alfonso, Antonio Jimeno

Journal:

Critical Reviews in Oncology/Hematology

Année:

2010

Fichier:

PDF, 455 KB

2010

9

Changes in antioxidative activities induced by Fe (II) and Fe (III) in cultured vero cells

C. García-Alfonso, J. López-Barea, P. Sanz, G. Repetto, M. Repetto

Journal:

Archives of Environmental Contamination and Toxicology

Année:

1996

Langue:

english

Fichier:

PDF, 672 KB

english, 1996

10

Metals are directly involved in the redox interconversion ofSaccharomyces cerevisiaeglutathione reductase

José Peinado, Javier Florindo, C. García-Alfonso, E. Martínez-Galisteo, Antonio Llobell, J. López-Barea

Journal:

Molecular and Cellular Biochemistry

Année:

1991

Langue:

english

Fichier:

PDF, 981 KB

english, 1991

11

NADPH and oxidized thioredoxin mediate redox interconversion of calf-liver andEscherichia colithioredoxin reductase

E. Martínez-Galisteo, C. García-Alfonso, C. Alicia Padilla, J. Antonio Bárcena, J. López-Barea

Journal:

Molecular and Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 775 KB

english, 1992

12

Colorectal cancer prevention

Montse Andreu, Mercè Marzo, Juanjo Mascort, Enrique Quintero, Pilar García-Alfonso, Cristina López-Ibor, Toni Castells, Pedro Pérez Segura

Journal:

Clinical and Translational Oncology

Année:

2009

Langue:

english

Fichier:

PDF, 118 KB

english, 2009

13

Adjuvant chemotherapy for stages II, III and IV of colon cancer

Cristina Grávalos, Ignacio García-Escobar, Pilar García-Alfonso, Javier Cassinello, Diego Malón, Alfredo Carrato

Journal:

Clinical and Translational Oncology

Année:

2009

Langue:

english

Fichier:

PDF, 240 KB

english, 2009

14

Recommendations and expert opinion on the treatment of locally advanced rectal cancer in Spain

Cristina Grávalos, Pilar García-Alfonso, Ruth Afonso, Virginia Arrazubi, Antoni Arrivi, Juan Carlos Cámara, Jaume Capdevila, Auxiliadora Gómez-España, Adelaida Lacasta, José Luis Manzano, Mercedes Sal

Journal:

Clinical and Translational Oncology

Année:

2011

Langue:

english

Fichier:

PDF, 177 KB

english, 2011

15

Induction oxaliplatin + 5-FU improves further the incidence of pT0 downstaged surgical specimens in ≥cT3 rectal cancer treated with preoperative chemoradiation

F Calvo, F Serrano, M Gomez-Espi, E Lozano, J Diaz-Gonzalez, J Arranz, P Garcia-Alfonso, E Alvarez

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

2003

Langue:

english

Fichier:

PDF, 45 KB

english, 2003

16

Capecitabine in combination with irinotecan (XELIRI), administered as a 2-weekly schedule, as first-line chemotherapy for patients with metastatic colorectal cancer: a phase II study of the Spanish GOTI group

Garcia-Alfonso, P, Muñoz-Martin, A, Mendez-Ureña, M, Quiben-Pereira, R, Gonzalez-Flores, E, Perez-Manga, G

Journal:

British Journal of Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 108 KB

english, 2009

17

Bevacizumab in combination with biweekly capecitabine and irinotecan, as first-line treatment for patients with metastatic colorectal cancer

García-Alfonso, P, Muñoz-Martin, A J, Alvarez-Suarez, S, Jerez-Gilarranz, Y, Riesco-Martinez, M, Khosravi, P, Martin, M

Journal:

British Journal of Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 243 KB

english, 2010

18

Weekly irinotecan (CPT-11) in 5-FU heavily pretreated and poor-performance-status patients with advanced colorectal cancer

M. Benavides, P. García-Alfonso, M. Cobo, A. Muñoz-Martín, S. Gil-Calle, F. Carabantes, E. Villar, J. Graupera, M. Balcells, G. Pérez-Manga

Journal:

Medical Oncology

Année:

2004

Langue:

english

Fichier:

PDF, 88 KB

english, 2004

19

Guidelines for biomarker testing in colorectal carcinoma (CRC): a national consensus of the Spanish Society of Pathology (SEAP) and the Spanish Society of Medical Oncology (SEOM)

Pilar García-Alfonso, Ramón Salazar, Jesús García-Foncillas, Eva Musulén, Rocío García-Carbonero, Artemio Payá, Pedro Pérez-Segura, Santiago Ramón y Cajal, Samuel Navarro

Journal:

Clinical and Translational Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 289 KB

english, 2012

20

Prevención del cáncer colorectal

Montserrat Andreu García, Mercè Marzo, Juanjo Mascort, Enrique Quintero, Pilar García-Alfonso, Cristina López-Ibor, Antoni Castells

Journal:

Atención Primaria

Année:

2009

Langue:

spanish

Fichier:

PDF, 393 KB

spanish, 2009

21

Prevención del cáncer colorrectal

Montserrat Andreu García, Mercè Marzo, Juanjo Mascort, Enrique Quintero, Pilar García-Alfonso, Cristina López-Ibor, Antoni Castells, Pedro Pérez Segura

Journal:

Gastroenterología y Hepatología

Année:

2009

Langue:

spanish

Fichier:

PDF, 336 KB

spanish, 2009

22

237 A phase I study of irinotecan (CPT-11) and capecitabina (XL) as second line treatment in advanced colorectal cancer

P. Garcia-Alfonso, A. Munoz, M. Méndez, S. Garcia-Adrian, P. Lopez-Criado, R. Alvarez, I. Siso, G. Pérez-Manga

Journal:

European Journal of Cancer Supplements

Année:

2003

Langue:

english

Fichier:

PDF, 160 KB

english, 2003

23

261 Phase I dose-escalationstudy with Raltitrexed (‘Tomudex’) combined with UFT in metastatic colorectal cancer

J.R. Mel, J.M. Vieitez, P. Garcia-Alfonso, M. Gonzalez-Baron, E. Alvarez, A. Jimenez-Lacave, J. Nuevo, R. Cajal, H. Bovio

Journal:

European Journal of Cancer Supplements

Année:

2003

Langue:

english

Fichier:

PDF, 319 KB

english, 2003

24

Purification and properties of bovine thioredoxin system

E. Martínez-Galisteo, C.A. Padilla, C. García-Alfonso, J. López-Barea, J.A. Bárcena

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 865 KB

english, 1993

25

Direct assay of glucose-6-P dehydrogenase and GSH-transferase in vero cells grown in microtitreplates as biomarkers of oxidative stress

Concepción García-Alfonso, Pilar Sanz, Manuel Repetto, Guillermo Repetto, Juan López-Barea

Journal:

Toxicology Letters

Année:

1996

Langue:

english

Fichier:

PDF, 124 KB

english, 1996

26

Preoperative chemoradiation with or without induction oxaliplatin plus 5-fluorouracil in locally advanced rectal cancer

Calvo, F.A., Sole, C.V., Serrano, J., Valle, E., Rodriguez, M., Muñoz-Calero, A., García-Sabrido, J.L., Garcia-Alfonso, P., Peligros, I., Alvarez, E.

Journal:

Strahlentherapie und Onkologie

Année:

2014

Langue:

english

Fichier:

PDF, 729 KB

english, 2014

27

Chemoradiation for resected pancreatic adenocarcinoma with or without intraoperative radiation therapy boost: Long-term outcomes

Calvo, Felipe A., Sole, Claudio V., Atahualpa, Freddy, Lozano, Miguel A., Gomez-Espi, Marina, Calin, Ana, García-Alfonso, Pilar, Gonzalez-Bayon, Luis, Herranz, Rafael, García-Sabrido, Jose Luis

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 497 KB

english, 2013

28

Reviewer list for 1994

Calvo, Felipe A., Sole, Claudio V., Atahualpa, Freddy, Lozano, Miguel A., Gomez-Espi, Marina, Calin, Ana, García-Alfonso, Pilar, Gonzalez-Bayon, Luis, Herranz, Rafael, García-Sabrido, Jose Luis

Journal:

Année:

1994

Fichier:

PDF, 55 KB

1994

29

The role of antiangiogenic agents in the treatment of patients with advanced colorectal cancer according toK-RASstatus

García-Alfonso, Pilar, Grande, Enrique, Polo, Eduardo, Afonso, Ruth, Reina, Juan José, Jorge, Mónica, Campos, Juan Manuel, Martínez, Virginia, Ángeles, Cristina, Montagut, Clara

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 394 KB

english, 2014

30

Comparison of the oxidative stress induced by two chemical species of iron in cultured vero cells

García-Alfonso, C., López-Barea, J, Sanz, P., Pepetto, G., Repetto, M.

Journal:

Toxicology Letters

Année:

1994

Langue:

english

Fichier:

PDF, 147 KB

english, 1994

31

18F-FDG PET bio-metabolic monitoring of neoadjuvant therapy effects in rectal cancer: Focus on nodal disease characteristics

Calvo, Felipe A., Cabezón, Luis, González, Carmen, Soria, Alicia, de la Mata, Dolores, Gómez-Espí, Marina, García-Alfonso, Pilar, Álvarez, Emilio, Carreras, José Luis

Journal:

Radiotherapy and Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 232 KB

english, 2010

32

Recomendación para la determinación de biomarcadores en el carcinoma colorrectal. Consenso Nacional de la Sociedad Española de Anatomía Patológica y de la Sociedad Española de Oncología Médica

Navarro, Samuel, Pérez-Segura, Pedro, Ramón y Cajal, Santiago, Salazar, Ramón, García-Foncillas, Jesús, Musulén Palet, Eva, García-Carbonero, Rocío, Payá, Artemio, García-Alfonso, Pilar

Journal:

Revista Española de Patología

Année:

2012

Fichier:

PDF, 464 KB

2012

33

Post-chemoradiation intraoperative electron-beam radiation therapy boost in resected locally advanced rectal cancer: Long-term results focused on topographic pattern of locoregional relapse

Sole, Claudio V., Calvo, Felipe A., Serrano, Javier, del Valle, Emilio, Rodriguez, Marcos, Muñoz-Calero, Alberto, Turégano, Fernando, García-Sabrido, Jose Luis, Garcia-Alfonso, Pilar, Peligros, Isabel

Journal:

Radiotherapy and Oncology

Année:

2014

Langue:

english

Fichier:

PDF, 683 KB

english, 2014

34

ABCB1 gene polymorphisms are associated with adverse reactions in fluoropyrimidine-treated colorectal cancer patients

Gonzalez-Haba, Eva, García, Maria I, Cortejoso, Lucia, López-Lillo, Carolina, Barrueco, Nélida, García-Alfonso, Pilar, Alvarez, Sonsoles, Jiménez, Jose L, Martín, María L, Muñóz-Fernández, Maria A, Sa

Journal:

Pharmacogenomics

Année:

2010

Langue:

english

Fichier:

PDF, 662 KB

english, 2010

35

Role of circulating tumor cells as prognostic marker in resected stage III colorectal cancer

Sotelo, M. J., Sastre, J., Maestro, M. L., Veganzones, S., Vieitez, J. M., Alonso, V., Gravalos, C., Escudero, P., Vera, R., Aranda, E., Garcia-Alfonso, P., Gallego-Plazas, J., Lopez, C., Pericay, C.,

Journal:

Annals of Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 251 KB

english, 2015

36

Updated guidelines for biomarker testing in colorectal carcinoma: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology

García-Alfonso, P., García-Foncillas, J., Salazar, R., Pérez-Segura, P., García-Carbonero, R., Musulén-Palet, E., Cuatrecasas, M., Landolfi, S., Ramón y Cajal, S., Navarro, S.

Journal:

Clinical and Translational Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 274 KB

english, 2015

37

Clinical management of regorafenib in the treatment of patients with advanced colorectal cancer

Sastre, J., Argilés, G., Benavides, M., Feliú, J., García-Alfonso, P., García-Carbonero, R., Grávalos, C., Guillén-Ponce, C., Martínez-Villacampa, M., Pericay, C.

Journal:

Clinical and Translational Oncology

Année:

2014

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2014

38

Neoadjuvant and conversion treatment of patients with colorectal liver metastasis: the potential role of bevacizumab and other antiangiogenic agents

García-Alfonso, Pilar, Ferrer, Ana, Gil, Silvia, Dueñas, Rosario, Pérez, María Teresa, Molina, Raquel, Capdevila, Jaume, Safont, María José, Castañón, Carmen, Cano, Juana María, Lara, Ricardo

Journal:

Targeted Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 321 KB

english, 2015

39

Differences in the Therapeutic Approach to Colorectal Cancer in Young and Elderly Patients

Serra-Rexach, J. A., Jimenez, A. B., Garcia-Alhambra, M. A., Pla, R., Vidan, M., Rodriguez, P., Ortiz, J., Garcia-Alfonso, P., Martin, M.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 240 KB

english, 2012

40

Prognostic Value ofBRAF,PI3K,PTEN,EGFRCopy Number, Amphiregulin and Epiregulin Status in Patients withKRASCodon 12 Wild-Type Metastatic Colorectal Cancer Receiving First-Line Chemotherapy with Anti-EGFR Therapy

P. Llovet, J. Sastre, J. S. Ortega, I. Bando, M. Ferrer, P. García-alfonso, O. Donnay, A. Carrato, A. Jiménez, E. Aranda, A. León, C. Grávalos, J. C. Cámara, J. Feliú, B. Sanchíz, T. Caldés, E. Díaz-r

Journal:

Molecular Diagnosis & Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2015

41

Biochemical bio markers of pollution in Algerian mouse (Mus spretus) to assess the effects of the AznalcÓllar disaster on Doñana Park (Spain)

J. Ruíz-Laguna, C. García-Alfonso,,

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 504 KB

english, 2001

42

Capecitabine and irinotecan with bevacizumab 2-weekly for metastatic colorectal cancer: the phase II AVAXIRI study

Garcia-Alfonso, Pilar, Chaves, Manuel, Muñoz, Andrés, Salud, Antonieta, García-Gonzalez, Maria, Grávalos, Cristina, Massuti, Bartomeu, González-Flores, Encarna, Queralt, Bernardo, López-Ladrón, Amelia

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 592 KB

english, 2015

43

SEOM clinical guidelines for diagnosis and treatment of metastatic colorectal cancer 2015

Aranda, E., Aparicio, J., Alonso, V., Garcia-Albeniz, X., Garcia-Alfonso, P., Salazar, R., Valladares, M., Vera, R., Vieitez, J. M., Garcia-Carbonero, R.

Journal:

Clinical and Translational Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 473 KB

english, 2015

44

Is regorafenib providing clinically meaningful benefits to pretreated patients with metastatic colorectal cancer?

García-Alfonso, P., Feliú, J., García-Carbonero, R., Grávalos, C., Guillén-Ponce, C., Sastre, J., García-Foncillas, J.

Journal:

Clinical and Translational Oncology

Année:

2016

Langue:

english

Fichier:

PDF, 429 KB

english, 2016

45

2123 Exposure-response (E-R) relationship of Ramucirumab (RAM) from a global, randomized, double-blind, Phase 3 study of patients (Pts) with advanced 2nd line colorectal cancer

Cohn, A. Lee, Yoshino, T., Obermannova, R., Bodoky, G., Prausova, J., Garcia-Carbonero, R., Ciuleanu, T. Eliade, Garcia-Alfonso, P., Portnoy, D.C., Van Cutsem, E., Yamazaki, K., Clingan, P.R., Polikof

Journal:

European Journal of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 64 KB

english, 2015

46

2122 Treatment outcomes according to extended RAS mutation testing in a phase II study of first-line mFOLFOX plus cetuximab followed by cetuximab in monotherapy as maintenance therapy or mFOLFOX plus cetuximab in patients with metastatic colorectal cancer: The MACRO-2 trial

Aranda, E., García-Alfonso, P., Benavides, M., Sanchez-Ruiz, A., Guillen-Ponce, C., Safont, M.J., Alcaide, J., Gomez, A., Lopez, R., Manzano, J.L., Mendez-Urena, M., Lopez, C., García-Paredes, B., Grá

Journal:

European Journal of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 73 KB

english, 2015

47

2033 Stage III colorectal cancer (CRC) in Spain: A retrospective analysis from 35 centres

Sotelo, L., Sastre, J., García-Paredes, B., Cabezas-Camarero, S., Vieitez, J.M., Alonso, V., Grávalos, C., Escudero, P, Vera, R., Aranda, E., García-Alfonso, P., Gallego-Plazas, J., Lopez, C., Pericay

Journal:

European Journal of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 60 KB

english, 2015

48

PO-0694: Coexpression of VEGFR and Ki67 on clinical outcome in patients with locally advanced rectal cancer

Solé, C., Calvo, F.A., Alvarez, E., Peligros, I., Gomez-Espi, M., Garcia-Alfonso, P., Ferrer, C., Ochoa, E., Herranz, R.

Journal:

Radiotherapy and Oncology

Année:

2013

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2013

49

Cost–effectiveness of screening for DPYD polymorphisms to prevent neutropenia in cancer patients treated with fluoropyrimidines

Cortejoso, Lucía, García-González, Xandra, García, María I, García-Alfonso, Pilar, Sanjurjo, María, López-Fernández, Luis A

Journal:

Pharmacogenomics

Année:

2016

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2016

50

D04Exposure-response (E-R) relationship of Ramucirumab (RAM) from a global, randomized, double-blind, Phase 3 study of patients (Pts) with advanced 2nd line colorectal cancer

Lonardi, S., Cohn, A.L., Yoshino, T., Obermannova, R., Bodoky, G., Prausová, J., Garcia-Carbonero, R., Ciuleanu, T., Garcia-Alfonso, P., Portnoy, D.C., Van Cutsem, E., Yamazaki, K., Clingan, P.R., Pol

Journal:

Annals of Oncology

Année:

2016

Langue:

english

Fichier:

PDF, 45 KB

english, 2016